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Inhibition of Epoxide Hydrolase 1 in the Treatment of Cardiovascular Diseases

This technology includes EPHX1/EPHX2 null mice and showed that disruption of both EPHX1 and EPHX2 almost completely abolished hydrolysis of several EETs which can be used in the treatment of cardiovascular diseases. EPHX 1 is significantly involved in EET hydrolysis, and we believe the combined use of EPHX1 and EPHX2 inhibitors would provide a better...

Published: 8/12/2024 | Inventor(s): Matthew Edin, Darryl Zeldin

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Category(s): Application > Research Materials, Application > Therapeutics, ResearchProducts > Animal Models, TherapeuticArea > Cardiology