Search Results - mingqian+feng

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Single-domain monoclonal antibodies for the treatment of hepatocellular carcinoma

Abstract: The National Cancer Institute seeks parties to license human monoclonal antibodies and immunoconjugates and co-develop, evaluate, and/or commercialize large-scale antibody production and hepatocellular carcinoma (HCC) xenograft mouse models. An advantage of these monoclonal antibodies as a potential therapeutic is their specificity, which...

Published: 5/21/2024 | Inventor(s): Mitchell Ho, Mingqian Feng, Dimiter Dimitrov, Heungnam Kim, Wei Gao

Keywords(s): Antibody-drug Conjugate, chimeric antigen receptor, HCC, hepatocellular carcinoma, IMMUNOTOXINS, Liver cancer

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology

Anti-Mesothelin Monoclonal Antibodies for the Treatment of Cancer

Abstract: The National Cancer Institute seeks parties interested in collaborative research to further co-develop monoclonal antibodies for the treatment of mesothelin-expressing cancers. The antibody was able to inhibit tumor growth in mouse xenograft models, and corresponding immunotoxins were able to inhibit tumor cell growth in vitro Mesothelin is...

Published: 5/21/2024 | Inventor(s): Mitchell Ho, Ira Pastan, Dimiter Dimitrov, Zhewei Tang, Mingqian Feng, Wei Gao

Keywords(s): Epitopes, MESOTHELIN, Monoclonal Antibodies

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Oncology