Search Results - pde4

1 Results

Sort By:

Radioligand for imaging brain PDE4 subtype D receptors with positron emission tomography

The technology relates to the first radioligands that can be used to image and quantify the enzyme phosphodiesterase subtype D (PDE4D). The PDE4D proteins have a role in carrying out signal transduction pathways in several cell types and is thought to be the key target of various antidepressants. Current work with imaging the radioligands in monkey...

Published: 7/25/2024 | Inventor(s): Sanjay Telu, Robert Innis, Robert Nugent, Mark Gurney, Xuesheng Mo, Victor Pike

Keywords(s): brain, D, Emission, IMAGING, PDE4, Positron, Radioligand, RECEPTORS, Subtype, tomography, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX

Category(s): Application > Diagnostics, Application > Research Materials, Application > Non-Medical Devices, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health, Application > Medical Devices, Application > Software / Apps