HOME
SEARCH
RSS FEED
SUBSCRIBE
Radioligand for imaging brain PDE4 subtype D receptors with positron emission tomography
Case ID:
TAB-3686
Web Published:
12/6/2022
Description:
The technology relates to the first radioligands that can be used to image and quantify the enzyme phosphodiesterase subtype D (PDE4D). The PDE4D proteins have a role in carrying out signal transduction pathways in several cell types and is thought to be the key target of various antidepressants. Current work with imaging the radioligands in monkey brains using positron emission tomography (PET) has been successful, and further work with humans is needed. An effective radioligand that can visualize PDE4D levels in human using PET can be useful in evaluation of health human subjects and in the development of PDE4D inhibitors.
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
Direct Link:
https://nih.technologypublisher.com/tech/Radioligand_for_imaging_brain_PDE4_s ubtype_D_receptors_with_positron_emission_tomography
Category(s):
Diagnostics
Research Materials
Non-Medical Devices
Neurology
Psychiatry/Mental Health
Medical Devices
Software / Apps
Bookmark this page
Download as PDF
For Information, Contact:
Anton Dawson
Technology Transfer and Patent Specialist
NIH Technology Transfer
301-496-6784
anton.dawson@nih.gov
Inventors:
Sanjay Telu
Robert Innis
Robert Nugent
Mark Gurney
Xuesheng Mo
Victor Pike
Keywords:
brain
D
Emission
IMAGING
PDE4
Positron
Radioligand
RECEPTORS
Subtype
tomography
VEXXXX
VNXXXX
WBXXXX
WIXXXX
XCXXXX
XFXXXX
Home
|
Search
|
RSS
|
Subscribe
© 2024. All Rights Reserved. Powered by
Inteum