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Smad4 Knockout (Smad4tm1Cxd) Mouse Model for Developmental Biology Studies

Smad4 knockout: Smad4 is essential for epiblast proliferation, egg cylinder formation and mesoderm induction in early embryogenesis. The TGF-beta-related superfamily plays an important role in multiple biological systems including embryogenesis. TGF-beta ligands activate specific receptors, which interact with specific Smad proteins, which in turn...

Published: 4/8/2024 | Inventor(s): Chuxia Deng

Keywords(s): DPC4-Null, Generation, IDXXXX, IXXXXX, Mice, SUPPRESSOR, tumor

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Research Materials, Application > Diagnostics