Search Results - therapeuticarea+%3e+ear%2c+nose%2c+%26+throat

30 Results

Sort By:

Systems and Methods to Automatically Detect Ellipsoid Zone Loss in SD-OCT Imaging

Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees for an automatic deep learning-based algorithm to detect and quantitate ellipsoid zone (EZ) loss in Spectral Domain Optical Coherence Tomography (SD-OCT) images. Description of Technology: The present disclosure generally relates a method of automatically...

Published: 3/11/2026 | Inventor(s): Wathudurage De Silva, Catherine Cukras

Keywords(s):

Category(s): Application > Software / Apps, TherapeuticArea, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

MODIFIED PIGMENT EPITHELIUM-DERIVED FACTOR PEPTIDES AND METHODS OF USE

Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of an eyedrop formulation to deliver a series of peptides as a gene-agnostic approach to treating inherited retinal diseases. Description of Technology: Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases...

Published: 3/11/2026 | Inventor(s): S. Patricia Becerra, Rolf Swenson, Natarajan Raju, Alexandra Bernardo-Colon, Carolyn Woodroofe, Burchelle Blackman

Keywords(s):

Category(s): Application > Therapeutics, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Suppression Of Uveitis By A STAT3 Single Domain Antibody

Summary: The National Eye Institute seeks research co-development partners and/or licensees for a STAT3 antibody that can suppress uveitis. Description of Technology: Uveitis is caused by inflammation in the eye that causes pain and reduce vision in affected patients. Rates of uveitis in the United States occurs 1 in every 200 people with eye-related...

Published: 4/22/2025 | Inventor(s): Charles Egwuagu, Sunanda Singh

Keywords(s):

Category(s): Application, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

Improved Methods For Cryopreservation Of Cells, Tissues, And Organs

Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...

Published: 5/15/2025 | Inventor(s): Jingxing Ou, Kiyoharu Miyagishima, Guanghui Jin, Wei Li, Lihao Ge

Keywords(s):

Category(s): Application, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

Using Artificial Intelligence To Diagnose Uveitis

Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can identify retinal vasculitis using color fundus images. Description of Technology: Uveitis is caused by inflammation in the eye that can cause pain and reduce vision. The rate of uveitis in the United States is 1 in every...

Published: 5/15/2025 | Inventor(s): Shilpa Kodati, Jongwoo Kim, Nam Nguyen

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

Using Artificial Intelligence To Predict The Risk Of Age-Related Macular Degeneration

Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can predict the probability of progression to late age-related macular degeneration. Description of Technology: In 2024, an estimated 200 million people worldwide suffer from age-related macular degeneration (AMD); projected...

Published: 5/15/2025 | Inventor(s): Emily Chew, Zhiyong Lu, Tiarnan Keenan, Wai Wong, Qingyu Chen, Elvira Agron

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

TYROSINASE Gene Therapy for Oculocutaneous Albinism type 1A

Summary: The National Eye Institute seeks research co-development partners and/or licensees for an adeno-associated viral gene therapy for Oculocutaneous Albinism type 1A. Description of Technology: Oculocutaneous albinism (OCA) is a genetically heterogeneous congenital disorder characterized by decreased or absent pigmentation in the hair,...

Published: 4/22/2025 | Inventor(s): Brian Brooks, Aman George

Keywords(s):

Category(s): Application, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing, TherapeuticArea > Rare/Neglected Diseases

Interleukin-27 Producing B-Cell Population and Uses Thereof

Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees to advance the production and uses of interleukin-27 (IL-27) producing B-regulatory cell (i27-Breg) therapy for immune related autoimmune disorders. These disorders include but are not limited, to age-related macular degeneration (AMD), graft-versus-host...

Published: 6/10/2025 | Inventor(s): Charles Egwuagu, Jin Choi

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Immunology, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

Using FDA-approved Small Molecule Drug Reserpine and related compounds (especially Halofantrine) To Protect Photoreceptors In Inherited Retinal Degenerations And Age-Related Macular Degeneration

Summary: The National Eye Institute seeks research co-development partners and/or licensees for a therapy using an FDA-approved small molecule drug reserpine (and related compounds especially halofantrine) that prevents photoreceptor cell death in retinal degenerations. Description of Technology: Inherited Retinal Degenerations (IRD), such as Leber...

Published: 2/20/2026 | Inventor(s): Anand Swaroop, Yu Holly Chen, Samantha Papal, Anupam Mondal, Manju Swaroop, Wei Zheng, Gregory Tawa, Wenwei Huang, Zhiji Luo

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing

Photoactivatable Lipid-based Nanoparticles as a Vehicle for Dual Agent Delivery

Abstract: The invention relates to novel lipid-based nanoparticles (liposomes) for use in targeted, on demand and on site drug delivery. The particles include a wall surrounding a cavity, wherein the wall is comprised of: A lipid bilayer comprising 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC), dipalmitoylphosphatidylcholine...

Published: 4/22/2025 | Inventor(s): Anu Puri, Robert Blumenthal, Amit Joshi, Darayash Tata, Mathias Viard

Keywords(s): Combination Therapy, Delivery Agent, Infections (bacteria and viruses), Lipid nanoparticle, liposome, On-demand Drug Release, photoactivation, therapeutic delivery

Category(s): TherapeuticArea > Infectious Disease, TherapeuticArea > Dermatology, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

1 2 3