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Search Results - therapeuticarea+%3e+ear%2c+nose%2c+%26+throat
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Methods To Regulate Metabolism For Treatment Of Neural Injuries and Neurodegeneration
Description of Technology: Axonal injury and subsequent neuronal death underpin the pathology of many neurological disorders from acute neural injuries (motor vehicle crashes, combat related injuries, traumatic brain injuries) to neurological diseases (multiple sclerosis, glaucoma). In the central nervous system (CNS), microglia help respond to CNS...
Published: 4/16/2026
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Updated: 4/16/2026
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Inventor(s):
Wei Li
,
Jingxing Ou
,
Tantai Zhao
Keywords(s):
Category(s):
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Ear, Nose, & Throat
,
TherapeuticArea > Neurology
,
Collaboration Sought > Licensing
Pigment Epithelium-Derived Factor Peptides and Their Use for Treating Retinal Degeneration
Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of an AAV2-based delivery system or an eyedrop formulation to deliver a Pigment Epithelium-Derived Factor (PEDF) peptide as a gene-agnostic approach to treating inherited retinal diseases. Description of Technology: Retinitis...
Published: 3/24/2026
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Updated: 3/13/2026
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Inventor(s):
S. Patricia Becerra
,
Alexandra Bernardo-Colon
,
Valeria Marigo
,
Andrea Bighinati
Keywords(s):
Category(s):
Application > Therapeutics
,
TherapeuticArea > Ear, Nose, & Throat
,
TherapeuticArea > Ophthalmology
,
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
Systems and Methods to Automatically Detect Ellipsoid Zone Loss in SD-OCT Imaging
Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees for an automatic deep learning-based algorithm to detect and quantitate ellipsoid zone (EZ) loss in Spectral Domain Optical Coherence Tomography (SD-OCT) images. Description of Technology: The present disclosure generally relates a method of automatically...
Published: 4/23/2026
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Updated: 3/11/2026
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Inventor(s):
Wathudurage De Silva
,
Catherine Cukras
Keywords(s):
Category(s):
Application > Software / Apps
,
TherapeuticArea
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
MODIFIED PIGMENT EPITHELIUM-DERIVED FACTOR PEPTIDES AND METHODS OF USE
Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of an eyedrop formulation to deliver a series of peptides as a gene-agnostic approach to treating inherited retinal diseases. Description of Technology: Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases...
Published: 3/11/2026
|
Updated: 3/11/2026
|
Inventor(s):
S. Patricia Becerra
,
Rolf Swenson
,
Natarajan Raju
,
Alexandra Bernardo-Colon
,
Carolyn Woodroofe
,
Burchelle Blackman
Keywords(s):
Category(s):
Application > Therapeutics
,
TherapeuticArea > Ear, Nose, & Throat
,
TherapeuticArea > Ophthalmology
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Suppression Of Uveitis By A STAT3 Single Domain Antibody
Summary: The National Eye Institute seeks research co-development partners and/or licensees for a STAT3 antibody that can suppress uveitis. Description of Technology: Uveitis is caused by inflammation in the eye that causes pain and reduce vision in affected patients. Rates of uveitis in the United States occurs 1 in every 200 people with eye-related...
Published: 4/16/2026
|
Updated: 11/21/2024
|
Inventor(s):
Charles Egwuagu
,
Sunanda Singh
Keywords(s):
Category(s):
Application
,
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Neurology
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
Improved Methods For Cryopreservation Of Cells, Tissues, And Organs
Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...
Published: 4/16/2026
|
Updated: 8/15/2024
|
Inventor(s):
Jingxing Ou
,
Kiyoharu Miyagishima
,
Guanghui Jin
,
Wei Li
,
Lihao Ge
Keywords(s):
Category(s):
Application
,
Application > Research Materials
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
Using Artificial Intelligence To Diagnose Uveitis
Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can identify retinal vasculitis using color fundus images. Description of Technology: Uveitis is caused by inflammation in the eye that can cause pain and reduce vision. The rate of uveitis in the United States is 1 in...
Published: 4/16/2026
|
Updated: 8/14/2024
|
Inventor(s):
Shilpa Kodati
,
Jongwoo Kim
,
Nam Nguyen
Keywords(s):
Category(s):
Application > Diagnostics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
Using Artificial Intelligence To Predict The Risk Of Age-Related Macular Degeneration
Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can predict the probability of progression to late age-related macular degeneration. Description of Technology: In 2024, an estimated 200 million people worldwide suffer from age-related macular degeneration (AMD); projected...
Published: 4/16/2026
|
Updated: 8/14/2024
|
Inventor(s):
Emily Chew
,
Zhiyong Lu
,
Tiarnan Keenan
,
Wai Wong
,
Qingyu Chen
,
Elvira Agron
Keywords(s):
Category(s):
Application > Diagnostics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
TYROSINASE Gene Therapy for Oculocutaneous Albinism type 1A
Summary: The National Eye Institute seeks research co-development partners and/or licensees for an adeno-associated viral gene therapy for Oculocutaneous Albinism type 1A. Description of Technology: Oculocutaneous albinism (OCA) is a genetically heterogeneous congenital disorder characterized by decreased or absent pigmentation in the hair, skin...
Published: 4/16/2026
|
Updated: 8/14/2024
|
Inventor(s):
Brian Brooks
,
Aman George
Keywords(s):
Category(s):
Application
,
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Ophthalmology
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
,
TherapeuticArea > Rare/Neglected Diseases
Interleukin-27 Producing B-Cell Population and Uses Thereof
Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees to advance the production and uses of interleukin-27 (IL-27) producing B-regulatory cell (i27-Breg) therapy for immune related autoimmune disorders. These disorders include but are not limited, to age-related macular degeneration (AMD), graft-versus-host...
Published: 4/16/2026
|
Updated: 8/14/2024
|
Inventor(s):
Charles Egwuagu
,
Jin Choi
Keywords(s):
Category(s):
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Neurology
,
TherapeuticArea > Immunology
,
TherapeuticArea > Ear, Nose, & Throat
,
Collaboration Sought > Licensing
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