Search Results - thomas+friedman

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Mouse model of TRIOBP Human Deafness for Research and Drug Discovery

This technology includes a mouse model of TRIOBP human deafness which can be used for research and treatment development for deafness. This model contains mutations altering the TRIOP-5 isoform.

Published: 8/12/2024 | Inventor(s): Thomas Friedman, Wade Chien, Inna Belyantseva

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, ResearchProducts > Animal Models

New Cancer Research Model: Spontaneously Transformed Mouse Epithelial Cancer Cell Lines

Abstract: The National Cancer Institute Cancer Genetics Branch is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize mouse epithelial cancer cell lines. Investigators at the NIH have created a collection of 45 mouse epithelial cancer cell lines derived from six...

Published: 7/25/2024 | Inventor(s): Hesed Padilla-Nash, Thomas Ried, Karen Hathcock, Nicole McNeil Ford

Keywords(s): Mouse Epithelial Cancer Cell Lines, Research Tools

Category(s): Application > Research Materials, TherapeuticArea > Oncology, Collaboration Sought > Licensing

Myosin-Based Protein-Protein Interaction Assay

Investigators at the National Institute on Deafness and Other Communication Disorders (NIDCD) have developed an assay for the detection of protein-protein interactions in living cells. This assay uses readily-available reagents and straightforward techniques that avoid the difficulty of purifying proteins or generating antibodies required for other...

Published: 7/25/2024 | Inventor(s): Thomas Friedman, Inna Belyantseva, Erich Boger

Keywords(s): [DC-023], [DC-024], [DC-025], [DC-026], [DC-027], [DC-028], [DC-029], 10, AC4XXX, AC5XXX, ACXXXX, assay, AXXXXX, cDNA, cDNAS, chimeric, Cloning, DsRed-tagged, ELEVEN, Flourescent, fluorescent, Fluorescent probe, Fourteen, Fusion, GFP, GFP-Myo, GFP-Myo10, GFP-MyolO, GFP-myosin, GFp-whirlin, GREEN, HEAVY, HMM, INTERACTION, KINESIN, Meromyosin, Mouse, MYOSIN, ONE, Patent Category - Biotechnology, Plasmic, PLASMID, Protein, PROTEIN-PROTEIN, PROTEIN-PROTEIN interactions, SIX, Sixteen, TAGGED, Twenty, Twenty-two, whirlin, X, XVa

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available