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Anti-Viral Polypeptide Griffithsin: Compounds, Compositions, and Methods of Use

Description of Technology: This technology describes additional methods of using the griffithsin anti-viral polypeptides described in related NCI invention (reference number E-106-2003). Specifically, this invention describes the use of GRFT to inhibit viral infection of hepatitis C viral infection, a severe acute respiratory syndrome (SARS) viral...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Barry O'Keefe, James McMahon, Toshiyuki Mori

Keywords(s): Anti-Viral, Corona virus, Ebola, Griffithsin, INFLUENZA, O’Keefe, SARS

Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Application > Therapeutics, Collaboration Sought > Licensing

An Anti-Viral Polypeptide: Griffithsin

Summary: Researchers at the NCI seek licensing and/or co-development research collaborations for anti-viral Griffithsin (GRFT) proteins. Description of Technology: Virus entry into a susceptible host cell is the first step in the formation of all viral diseases. Controlling viral infections by disrupting viral entry is advantageous for antibody-mediated...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Michael Boyd, Toshiyuki Mori, Barry O'Keefe

Keywords(s): Griffithsin, O'Keefe, SARS, Severe acute respiratory syndrome

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing