Search Results - un-kyung+kim

4 Results

Sort By:

Discovery of Novel SHT (SHT6) Compounds for the Treatment of Central Nervous System-related Diseases

This technology includes novel compounds which can be expected to selectively target the 5HT6 receptor, which is implicated in CNS-related diseases. In particular 5HT6 antagonism has been implicated in cognitive impairment, AD/PD and drug abuse/alcohol abuse related disorders. 5HT6 compounds have also shown to reduce appetite and induce weight loss....

Published: 8/12/2024 | Inventor(s): Malliga Iyer, Kyu Kim

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, ResearchProducts > Human Cell Lines, TherapeuticArea > Endocrinology, TherapeuticArea > Metabolic Disease, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health

Human Sweet and Umami Taste Receptor Variants

The complexity of taste discrimination (salty, sour, sweet, umami and bitter) varies between human individuals and populations. Sweet and umami (the taste of glutamate) tastes play a major role in the perception of calorically-rich and essential nutrients and there are well-documented differences in individual perception of sweet and umami flavorings,...

Published: 7/25/2024 | Inventor(s): Un-kyung Kim, Dennis Drayna

Keywords(s): AC4XXX, ACXXXX, AXXXXX, GENOTYPES, Haplotypes, Human, ICXXXX, IXXXXX, population genetics, SNPs, sweet taste, TASTE, taste evaluation, taste receptors, umamai taste, VARIANTS

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics

Haplotypes of Human Bitter Taste Receptor Genes

Bitter taste has evolved in mammals as a crucial, important warning signal against ingestion of poisonous or toxic compounds. However, many beneficial compounds are also bitter, and taste masking of bitter tasting pharmaceutical compounds is a billion dollar industry. The diversity of compounds that elicit bitter-taste sensations is very large and...

Published: 7/25/2024 | Inventor(s): Un-kyung Kim, Dennis Drayna

Keywords(s): AC4XXX, ACXXXX, AXXXXX, Bitter, bitter taste, Chromosome 22 ring, flavor evaluation, Haplotypes, Human, ICXXXX, IXXXXX, population genetics, R 22, RECEPTOR, SNPs, TASTE, taste masking, taste receptors, VARIANTS

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Research Materials, Application > Diagnostics

Phenylthiocarbamide (PTC) Taste Receptor

Bitter taste has evolved in mammals as a central warning signal against ingestion of poisonous or toxic compounds. However, many beneficial compounds are also bitter and taste masking of bitter tasting pharmaceutical compounds is a billion dollar industry. The diversity of compounds that elicit bitter-taste sensations is vast and more than two dozen...

Published: 7/25/2024 | Inventor(s): Un-kyung Kim, Dennis Drayna

Keywords(s): bitter taste, ICXXXX, IXXXXX, Phenylthiocarbamide, POLYMORPHISMS, PTC, RECEPTOR, SNPs, taste masking

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics