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VAC-BAC Shuttle Vector System for Generating Recombinant Poxviruses

This invention relates to a VAC-BAC shuttle vector system for the creation of recombinant poxviruses from DNA cloned in a bacterial artificial chromosome. A VAC-BAC is a bacterial artificial chromosome (BAC) containing a vaccinia virus genome (VAC) that can replicate in bacteria and produce infectious virus in mammalian cells.

Published: 7/25/2024 | Inventor(s): Arban Domi, Bernard Moss

Keywords(s): Chromosome 7, monosomy, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DCXXXX, Deletion 7, DXXXXX, SHUTTLE, System, VAC-BAC, Vector

Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease