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High-Affinity Mouse Monoclonal Antibodies to GPC-3 for Liver Cancer Research

Abstract: The National Cancer Institute Laboratory of Molecular Biology seeks parties for collaborative research to co-develop and commercialize antibody drug/toxin conjugates as liver cancer therapy and diagnostics. There is great interest and value in developing more sensitive and efficient agents for earlier detection of hepatocellular cancer (HCC). ...

Published: 5/21/2024 | Inventor(s): Mitchell Ho, Yen Phung, Wei Gao, Yifan Zhang

Keywords(s): ANTIBODY, GLYCOPROTEIN, Glypican-3, GPC3, HCC, hepatocellular carcinoma, liver, monoclonal

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing

High-Affinity Rabbit Monoclonal Antibodies for Cancer Treatment

Abstract: Mesothelin is a cell surface protein that is highly expressed in aggressive cancers, such as malignant mesothelioma, ovarian cancer and pancreatic cancer, lung cancer, breast cancer, cholangiocarcinoma, bile duct carcinoma and gastric cancer. Because of this selective expression, mesothelin is an excellent candidate for targeted therapeutics,...

Published: 5/21/2024 | Inventor(s): Mitchell Ho, Ira Pastan, Yen Phung, Yifan Zhang, Raffit Hassan, Wei Gao

Keywords(s): Epitope, MESOTHELIN

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics