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A Method to Expand a Population of Regulatory T Cells Optimal for the Treatment of Autoimmune Diseases

The transfusion of regulatory T cells (Tregs) has been used in the clinic to successfully prevent graft vs. host disease and is currently being evaluated in the treatment of other autoimmune diseases, such as organ graft rejection, type 1 diabetes and multiple sclerosis. Prior to transfusion, adoptive regulatory T cell transfer requires the expansion...

Published: 7/25/2024 | Inventor(s): Ethan Shevach, Yong Chan Kim

Keywords(s): Cells, FOXP3+, Helios-expressing, Human, IBXXXX, IDXXXX, IXXXXX, oligonucleotides, Random-sequenced, Regulatory, Stabilization, T, Usingrandom-sequenced

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics