Antagonist of A3 Adenosine Receptor Fluorescent Probes for the Study of Diseases that Involve A3 Signaling

Description:
This molecular probe may serve as a companion tool to identify and stratify patient populations based on the prevalence of the target A3 adenosine receptors.

Small molecule drugs, A3AR-selective agonists, are currently in advanced clinical trials for the treatment of hepatocellular carcinoma, autoimmune inflammatory diseases, such as rheumatoid arthritis, psoriasis, and dry eye disease, and other conditions.
Patent Information:
For Information, Contact:
Betty Tong
Technology Licensing Specialist
NIH Technology Transfer
301-451-7836
tongb@niddk.nih.gov
Inventors:
Kenneth Jacobson
Keywords:
A3
ADENOSINE
ANTAGONISTS
BINDING
CA1CXX
CA1XXX
CAXXXX
CXXXXX
fluorescent
IA2XXX
IA3XXX
IAXXXX
IXXXXX
Molecular
Novel
Probes
RECEPTOR
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