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Floxed Targeted Mouse Strain for Use in Conditional Deletion of the Irf8 Gene
Case ID:
TAB-3383
Web Published:
12/6/2022
Description:
IRF8, a member of interferon regulatory factor (IRF) family of transcription factors is a novel intrinsic transcriptional inhibitor of TH17-cell differentiation. TH17-cells are believed to be involved in the pathogenesis of various autoimmune/inflammatory diseases. These materials could be used to help define patterns of gene expression important for the development and function of cells including possible contributions to understanding: normal immune responses, inflammatory conditions, autoimmunity and anti-viral responses.
Patent Information:
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Patent No.
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Direct Link:
https://nih.technologypublisher.com/tech/Floxed_Targeted_Mouse_Strain_for_Use _in_Conditional_Deletion_of_the_Irf8_Gene
Category(s):
Collaboration
Research Materials
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For Information, Contact:
Dawn Taylor-Mulneix
TTPS
NIH Technology Transfer
301-761-6958
dawn.taylor-mulneix@nih.gov
Inventors:
Herbert Morse
Keywords:
Approved
Conditional
Deletion
Design
Development
Gene
Generate
IRF8
Knockout
Listed LPM Vepa as of 4/15/2015
Mouse
Need
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
RECOGNIZED
RXXXXX
Strain
Used
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