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Rabies Vaccine for the Oral Immunization of Domesticated Animals, Wildlife and Feral Animals
Case ID:
TAB-2785
Web Published:
12/6/2022
Description:
This invention, developed by the CDC and collaborators, entails a live, attenuated recombinant rabies virus vaccine that can elicit an effective anti-rabies immune response in animal recipients. Inoculation with a live, attenuated, rabies virus allows for the optimized production of immunity in the absence of pathogenicity. Oral administration of rabies vaccines is often a preferred route of vaccine delivery because it is most effective in wildlife. Unfortunately, availability of an oral vaccine for canines has been a significant hurdle to date.
This vaccine technology could be used for immunization of stray dogs by an oral route. In developing nations, more than 90% of human exposure events and 99% of human deaths due to rabies are caused by rabid dogs. Using this vaccine with a broadly implemented oral vaccination strategy provides a promising opportunity for reducing transmission of rabies between stray dogs and, thereby, increasing protection for people.
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Direct Link:
https://nih.technologypublisher.com/tech?title=Rabies_Vaccine_for_the_Oral_Im munization_of_Domesticated_Animals%2c_Wildlife_and_Feral_Animals
Category(s):
Collaboration
Infectious Disease
Occupational Safety and Health
Therapeutics
Vaccines
Consumer Products
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For Information, Contact:
Jeremiah Mitzelfelt
NIH Technology Transfer
301-443-8518
jeremiah.mitzelfelt@nih.gov
Inventors:
Charles Rupprecht
Keywords:
CDC Docket Import
CDC Docket Import NP
DC5BXX
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Dogs
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ENGINEERED
GENETICALLY
Immunization
rabies
recombinant
Stray
Vaccine
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VOXXXX
WFXXXX
Wildlife
WJXXXX
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YBXXXX
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