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Modified griffithsin tandemers for enhanced activity and reduced viral aggregation

Abstract: Griffithsin (GRFT) is a lectin with potent antiviral properties that is capable of preventing and treating infections caused by a number of enveloped viruses (including HIV, SARS, HCV, HSV, and Japanese encephalitis) and is currently in clinical development as an anti-HIV microbicide. In addition to its broad antiviral activity, GRFT is stable...

Published: 4/8/2024 | Inventor(s): Barry O'Keefe, Alexander Wlodawer, Tinoush Moulaei

Keywords(s): ANTIVIRAL, mGRFT tandemers

Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, Application > Therapeutics