Search Results - brian+safer

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The invention described and claimed in this patent application relates to the delivery of heterologous nucleic acids or genes to particular target cells. In particular, the application relates to methods of delivering a heterologous nucleic acid or gene of interest to particular target cells using Adeno-Associated Virus of serotype 4 (AAV4). The particular...

Published: 7/25/2024 | Inventor(s): Robert Kotin, Brian Safer, Beverly Davidson, John (Jay) Chiorini

Keywords(s): AAV, AAV4, brain, CB2AXX, CBXXXX, CXXXXX, ependymal cells, GB2A2X, GB2XXX, GENE THERAPY, Listed LPM Reichman as of 4/15/2015, NB1XXX, NBXXXX, NXXXXX, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, SACGHS DNA Patent Initial Set, USES, viral vector

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics, TherapeuticArea > Neurology

Cannula for Pressure Mediated Drug Delivery

Available for licensing are methods and devices for selectively delivering therapeutic substances to specific histological or microanatomical areas of organs (e.g., introduction of the therapeutic substance into a hollow organ space such as the hepatobiliary duct or the gallbladder lumen) at a controlled pressure, volume and/or rate which allows the...

Published: 7/25/2024 | Inventor(s): Randall Clevenger, John Deleonardis, Robert Hoyt, Robert Lutz, Brian Safer

Keywords(s): AB3CXX, AB3FXX, AB3XXX, ABXXXX, AXXXXX, Delivery, Mediated, PCT/US99/11277, PRESSURE, Psoukas, SELECTIVE, SUBSTANCES, therapeutic

Category(s): Collaboration Sought > Licensing

AAV4 Vector And Uses Thereof

These patent applications describe the cloning and characterization of the full-length genome of adeno-associated virus type 4 (AAV4). AAV4, like other members of the AAV family, may be useful as a vector for gene therapy. When compared to AAV2, AAV4 may be better suited as a vector due to its larger size -- which permits efficient encapsidation of...

Published: 7/25/2024 | Inventor(s): John (Jay) Chiorini, Robert Kotin, Brian Safer

Keywords(s): GB3XXX, GBXXXX, GXXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics