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A Novel Scaffold for Multivalent Display of Ligands

Multivalent interactions are important in cell attachment, wound healing and immune responses. Such interactions are associated with cancer metastasis, blood clotting and the generation of antibodies from a vaccination. Mimicking multivalent interactions on a synthetic scaffold is challenging especially when large numbers of ligands (such as 5 or more)...

Published: 10/28/2024 | Inventor(s): Daniel Appella

Keywords(s): AAXXXX, AXXXXX, Based, Chain-Modified, DISPLAY, LIGANDS, MULTIVALENT, Nanostructures, PNA, PNAfor, PROGRAMMABLE, Self-assembled, SIDE, Sidechain-Modified, YXXXXX

Category(s): Collaboration Sought > Collaboration