Search Results - christina+teng

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Developing a Stable Cell as a Screening Tool for Environmental Chemicals

This technology includes a stable cell line (293T2-PGC) which has an intact PGC-1 alpha/ERR-alpha pathway to screen for environmental chemicals. The estrogen-related receptor alpha (ERR-alpha) and proliferator-activated receptor gamma coactivator - 1alpha (PGC-1 alpha) play critical roles in the control of several physiological functions, including...

Published: 8/12/2024 | Inventor(s): Christina Teng

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, ResearchProducts > Human Cell Lines

The estrogen-related receptor alpha (ERRalpha) and proliferator-activated-receptor-gamma coactivator-1alpha (PGC-1alpha) play major roles in transcriptional control of cellular energy metabolism. In particular ERRs are required for the response to various environmental challenges that require high energy levels by the organism. As central regulators...

Published: 7/25/2024 | Inventor(s): Negin Martin, Christina Teng

Keywords(s): \Related, Cell, COACTIVATOR, ERR, estrogen, Gamma, Lines, PGC/ERR, Proliferator-activated, RECEPTOR, RELATED, -related, REPORTER, STABLE, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Antibody to Estrogen Related Receptor alpha

Estrogen related receptor alpha (ERRalpha) is a family member of the steroid/thyroid nuclear receptor superfamily. Estrogen related receptors are thought to regulate similar target genes in the absence of known ligands. For example, the inventors previously cloned the human estrogen receptor-related orphan receptor alpha1 cDNA and demonstrated that...

Published: 7/25/2024 | Inventor(s): Christina Teng

Keywords(s): AC5XXX, ACXXXX, AXXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Mouse Lactoferrin Antibody

Lactoferrin, an iron-binding glycoprotein, kills bacteria and modulates inflammatory and immune responses. It is expressed in mucosa membrane and is present in saliva, tears, vaginal secretion and neutrophils. It modulates immune and inflammatory response by down-regulating several cytokines. Therefore, lactoferrin is an important protein in first...

Published: 7/25/2024 | Inventor(s): Christina Teng

Keywords(s): AC5XXX, ACXXXX, AXXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Methods of Screening for Risk of Cancer Using Human Lactoferrin DNA Probe or Primer

While normal breast ductal epithelium and neutrophilic granulocytes contain lactoferrin, their malignant counterparts frequently do not. The NIH announces primers or probes corresponding to the human lactoferrin gene, its promoter region, and its protein product, obtained from human breast tissue. The lactoferrin primer or probes can be used to screen...

Published: 4/8/2024 | Inventor(s): Christina Teng, Timothy Panella

Keywords(s): CAXXXX, CXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics