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Novel Targets to Prevent Borrelia burgdorferi Infection and Lyme Disease

B. burgdorferi-infected ticks can cause Lyme disease in mammalian hosts. This technology relates to the use of B. burgdorferi outer surface proteins (BBA64 and BBA66) as Lyme disease vaccine candidates. In vivo animal studies demonstrate these outer surface proteins inhibit tick-to-host B. burgdorferi transmission. Presently, there is no vaccine approved...

Published: 4/8/2024 | Inventor(s): Robert Gilmore

Keywords(s): BBA66, BORRELIA, BURGDORFERI, CDC Docket Import, CDC Docket Import CDC Prosecuting, COMPONENT, DA3XXX, DAXXXX, DB3XXX, DBXXXX, DC4XXX, DXXXXX, Gene, Infectivity, MAMMALIAN, Necessary, PATHOGEN, TICK, TRANSMISSION, Vector, Via

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines, Application > Diagnostics

Signal-to-Noise Enhancement in Imaging Applications Using a Time-Series of Images

The invention offered for licensing relates to the field of imaging and specifically to the field of medical imaging. The apparatus and method of the invention provide for noise reduction in imaging applications that use a time-series of images. In one embodiment of the invention, a time-series of images is acquired using a same imaging protocol of...

Published: 7/25/2024 | Inventor(s): Vinay Pai, Han Wen

Keywords(s): Acquisitions, analysis, COMBINED, COMPONENT, ENHANCEMENT, IA4BXX, IA4XXX, IAXXXX, IMAGING, INTENSITY, IXXXXX, LOW, Magnetic, Maximal, Method, Patent Category - Mech/Elect/Soft, PCA, PRINCIPAL, PROJECTION, Resonance, Signal, Signal-to-Noise, TEMPORAL, tMIP

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics