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Plasmid Useful in Transplantation Therapy for Age-Related Eye Disease

Researchers have developed a green fluorescent protein (GFP) based plasmid that can be used to detect differentiated retinal pigment epithelium (RPE) cells. RPE is a layer of cells located behind the eye that becomes damaged in age-related macular degeneration (AMD). Current cell based therapies for treating AMD focus on generating RPE cells from...

Published: 4/8/2024 | Inventor(s): Kapil Bharti

Keywords(s): Cell, CONSTRUCT, Generating, GFP-based, IBXXXX, IDXXXX, IXXXXX, Lines, REPORTER, RPE-specific, Stem

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics

Construct for Tetracycline Inducible Podocyte Specific Gene Expression in Mice

The National Institutes of Health announces the generation of a construct by ligating 2.5kb human podocin promoter sequence to gene encoding reverse tetracycline-controlled transcriptional activator which enables tetracycline-inducible podocyte specific gene of interest expression with another construct consisting of tetracycline responsive element,...

Published: 7/25/2024 | Inventor(s): Jeffrey Kopp

Keywords(s): CONSTRUCT, Expression, Gene, IDXXXX, INDUCIBLE, IXXXXX, Mice, Podocyte, Specific, Tetracycline

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics