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Coumarin Luciferins and Mutant Luciferases for Bioluminescence Imaging

Summary: Researchers at UCI and NCI seek licensing to adopt new applications for a family of far-red to near-infrared emission coumarin-based luciferins (CouLuc) with complementary mutant enzymes. Description of Technology: Bioluminescence imaging with luciferin-luciferase pairs is a well-established technique for tracking cells and other biological...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Martin Schnermann, Donald Caldwell, Jennifer Prescher, Zi Wei Yao, Anna Love

Keywords(s): CouLuc, Luciferases, Luciferins, Near-infrared, NIR, Optical Imaging, Schnermann

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Therapeutics