Search Results - dennis+klinman

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Nanoparticle delivery of lung cancer therapeutic

Abstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in developed countries. Despite the availability of several synergistic, targeted therapy regiments, the 5-year survival rate for NSCLC is only 15%. The poor prognosis of NSCLS is due in part to limitations of current treatments, which do not trigger an immune...

Published: 5/22/2024 | Inventor(s): Dennis Klinman, Takashi Sato (Unable To Locate)

Keywords(s): Immunotherapy, Nanoparticle, Non-small cell lung cancer, NSCLC

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology

Topical Antibiotic for Faster Wound Healing

Abstract: Currently available topical antibiotic formulations effectively eliminate bacteria at a wound site. Eliminating bacteria in the wound also eliminates the molecular signals present in bacterial DNA that stimulate the immune system's wound healing processes. Without these signals, the rate of wound healing is diminished. The present technology...

Published: 5/22/2024 | Inventor(s): Dennis Klinman, Hiroyasu Ito

Keywords(s): CpG motifs, Immunostimulation, ODN., Oigodeoxynucleotides, TLR7, TLR9, Wound healing

Category(s): TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Therapeutics