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Vaccines for HIV

Abstract: The development of an effective HIV vaccine has been an ongoing area of research. The high variability in HIV-1 virus strains has represented a major challenge in successful development. Ideally, an effective candidate vaccine would provide protection against the majority of clades of HIV. Two major hurdles to overcome are immunodominance...

Published: 5/22/2024 | Inventor(s): Barbara Felber, George Pavlakis, Antonio Valentin, James Mullins

Keywords(s): ENV, GAG, HIV Vaccine, immunogenic conserved elements

Category(s): Collaboration Sought > Collaboration, Application > Vaccines, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Combined RNA and DNA Vaccination Strategy for Improving the Vaccine Immune Response

The development of an effective HIV vaccine has been ongoing. HIV sequence diversity and immunodominance are major obstacles in the design of an effective vaccine. Researchers at the National Cancer Institute (NCI) developed a novel vaccine strategy combining both DNA and mRNA vaccination to induce an effective immune response. This combination strategy...

Published: 5/22/2024 | Inventor(s): Barbara Felber, George Pavlakis

Keywords(s): CANCER VACCINE, DNA vaccine, ENV, Felber, GAG, HIV, Infectious Disease, Nci, Pavlakis, RNA Vaccine, SARS-CoV-2, Vaccine

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Vaccines, TherapeuticArea > Infectious Disease