Search Results - hiv+vaccine

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Vaccines for HIV

Abstract: The development of an effective HIV vaccine has been an ongoing area of research. The high variability in HIV-1 virus strains has represented a major challenge in successful development. Ideally, an effective candidate vaccine would provide protection against the majority of clades of HIV. Two major hurdles to overcome are immunodominance...

Published: 5/22/2024 | Inventor(s): Barbara Felber, George Pavlakis, Antonio Valentin, James Mullins

Keywords(s): ENV, GAG, HIV Vaccine, immunogenic conserved elements

Category(s): Collaboration Sought > Collaboration, Application > Vaccines, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Novel Fusion Proteins for HIV Vaccine

Abstract: Development of successful HIV vaccine immunogens continues to be a major challenge. Although gp120 was identified as having significant potential as a vaccine immunogen, attempts to elicit broadly neutralizing antibodies using recombinant gp120 failed. The highly flexible gp120 may present numerous conformations to the humoral immune system...

Published: 7/25/2024 | Inventor(s): Dimiter Dimitrov, Weizhao Chen

Keywords(s): ANTIBODY, CD4, Dimitrov, fusion protein, gp120, HIV Vaccine

Category(s): TherapeuticArea > Immunology, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing