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Fgfr2 Knockout (Fgfr2tm1Cxd) Mouse Model for Developmental Biology Studies

FGFR2 knockout is an embryonic lethal mutation and blocks limb bud initiation. Fibroblast Growth Factor Receptor 2 (FGFR2) is a high affinity receptor for several members of the FGF family. The FGFR2 gene was inactivated by deleting the entire immunoglobulin-like domain of the receptor which is critical for FGF binding and FGFR2 activity. Embryos...

Published: 7/25/2024 | Inventor(s): Chuxia Deng

Keywords(s): FGFR2, IDXXXX, IXXXXX, Knock, Mouse, Tm1Cxd

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics