Search Results - htlv-2

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Accelerated Vaccination Strategies to Provide Protection Against Viral Infections

The technology described in this patent application relates to recombinant viruses for use as vaccines. These viruses contain a single or plurality of sequences encoding antigens from pathogenic viruses heterologous to the recombinant virus. The antigenic sequences from pathogens such as influenza, RSV, measles, HPV, Epstein-Barr, Lassa, Polio, West...

Published: 7/25/2024 | Inventor(s): Gary Nabel

Keywords(s): DC5BXX, DCXXXX, Dengue (Flaviviridae), DXXXXX, Hepatitis A, Hepatitis D, Hepatitis E, HTLV-1, HTLV-2, HTLV-3, Human T Cell Leukemia Virus 1, Human T-cell leukemia viruses type 2, Human T-lymphotropic virus type 3, MEASLES

Category(s): Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease

Increased Protein Expression Vector for Vaccine Applications

An expression vector with a unique promoter that results in higher level of protein expression than vectors currently in use is available for licensing from the NIH. The elevated levels of expression are achieved through use of a specific promoter, known as CMV/R, in which the Human T-Lymphotrophic Virus (HTLV-1) Long Terminal Repeat (LTR) R-U5 region...

Published: 7/25/2024 | Inventor(s): Gary Nabel, Zhi-yong Yang

Keywords(s): DCXXXX, DXXXXX, HTLV-1, HTLV-2, HTLV-3, Human T Cell Leukemia Virus 1, Human T-cell leukemia viruses type 2, Human T-lymphotropic virus type 3, WEST NILE VIRUS

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines

Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway

The invention provides identification methods for agents which inhibit the Jak-STAT signaling transduction pathway. Drugs identified by these methods are candidates for the treatment of proliferative disorders dependent on the Jak-STAT pathway, including those caused by HTLV-1. In addition, such agents may be potent immunosuppressive drugs with potential...

Published: 7/25/2024 | Inventor(s): Warren Leonard

Keywords(s): HTLV-1, HTLV-2, HTLV-3, Human T Cell Leukemia Virus 1, Human T-cell leukemia viruses type 2, Human T-lymphotropic virus type 3, IBXXXX, ICXXXX, IXXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics