Search Results - human+papillomavirus

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Agonist Epitopes for the Development of a Human Papillomavirus (HPV) Therapeutic Vaccine

Abstract: Human papillomavirus (HPV) has been associated with the cause of several cancer types, including cervical, anal, and head and neck cancers. There has been great success in preventing HPV infections with the development of prophylactic HPV vaccines, Gardasil and Cervarix. However, these vaccines have only been shown to prevent HPV infection...

Published: 4/8/2024 | Inventor(s): Jeffrey Schlom, Kwong-Yok Tsang

Keywords(s): Agonist Epitope, CTL, Cytotoxic T Lymphocytes, HPV, Human Papillomavirus, Schlom, Therapeutic Vaccine

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics

T-cell Receptor Targeting Human Papillomavirus-16 E7 Oncoprotein

Abstract: Human papillomavirus (HPV) is a group of human viruses known to cause various malignancies. Of the group, HPV-16 is the most prevalent strain – an estimated 90% of adults have been exposed. HPV-16 is also the strain most commonly associated with malignancy, causing the vast majority of cervical, anal, vaginal, vulvar, and penile cancers. Currently,...

Published: 4/8/2024 | Inventor(s): Christian Hinrichs, Steven Rosenberg

Keywords(s): act, adoptive cell therapy, Cervical cancer, E7, HLA-A*02, HPV, Human Papillomavirus, Major Histocompatibility Complex, MALIGNANCY, MHC, ONCOPROTEIN, Rosenberg, T Cell Receptor, TCR

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease

T-cell Receptor Targeting Human Papillomavirus-16 E6 Oncoprotein

Published: 4/8/2024 | Inventor(s): Christian Hinrichs, Steven Rosenberg

Keywords(s): act, adoptive cell therapy, Cervical cancer, E6, HLA-A*02, HPV, Human Papillomavirus, Major Histocompatibility Complex, MALIGNANCY, MHC, ONCOPROTEIN, Rosenberg, T Cell Receptor, TCR

Category(s): TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics