Search Results - jesus+valenzuela

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Vaccines Comprising Sand Fly Salivary Proteins for Control of Leishmania Infection

This invention relates to the use of several peptides from the salivary glands of various sand fly species for the control of leishmania infection. Many of these peptides were shown to be effective in eliciting potent immune responses in animal models and are excellent candidates for the development of vaccines against the disease. A vaccine comprising...

Published: 7/25/2024 | Inventor(s): Jesus Valenzuela

Keywords(s): Adn, America, ARIASI, Cellular, Chagase, DA2XXX, DAXXXX, DB2XXX, DBXXXX, DC2XXX, DCXXXX, DDXXXX, Dogs, DXXXXX, Efficient, ELICIT, Fly, Identification, IFN-gamma, Immunity, Infantum, KILLING, Latin, LEISHMANIA, LEISHMANIASIS, Leishmaniasis (Leishmania sp.), Listed LPM Stansberry as of 4/15/2015, LJL143, LJM17, Longipalpis, Lutzomyiz, Method, P., Patent Category - Biotechnology, PERNICIOSUS, POLYPEPTIDES, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, production, proteins, RESULTING, Salivary, SAND, That, Vector, Visceral, WIPO Re:search

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease

Anti-Arthropod Vector Vaccines, Methods of Selecting, and Uses Thereof

Leishmania parasites are transmitted to their vertebrate hosts by infected phlebotomine sand fly bites. Sand fly saliva is known to enhance Leishmania infection, while immunity to the saliva protects against infection. This invention claims nine major salivary proteins from the sand fly vector of Leishmania major, Phlebotomus papatasi, nucleic acids...

Published: 7/25/2024 | Inventor(s): Jesus Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose Ribeiro

Keywords(s): DB3XXX, DBXXXX, DC4XXX, DCXXXX, DXXXXX

Category(s): Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Therapeutics

Ixodes scapularis Tissue Factor Pathway Inhibitor

Ixodes scapularis is a blood-sucking tick and the principal vector of Lyme disease, a spirochetal illness caused by Borrelia burgdorferi and now the most common vector-borne infection in the United States; more than 50,000 cases have been reported during the last ten years. The salivary gland of I. scapularis has a number of pharmacologically active...

Published: 7/25/2024 | Inventor(s): Ivo Francischetti, Jesus Valenzuela, Jose Ribeiro

Keywords(s): Borreliosis, DB3XXX, DBXXXX, DC4XXX, DCXXXX, DXXXXX, Lyme Disease

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines