Search Results - juan+rivera

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A Phospho-specific antibody to Fc “epsilon” R1 “gamma” as a Diagnostic Tool for Allergic Reactions

This technology includes a mouse monoclonal antibody that recognizes the phosphorylated form of the FceRiy which could be used as a diagnostic tool during allergic reactions. The FcERI is central to the activation of mast cells and basophils and activation of this receptor induces these cells to secrete mediators that cause allergic symptoms. This antibody...

Published: 7/30/2024 | Inventor(s): Juan Rivera, Ryo Suzuki

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing

Potential Use of anti-IgE in the Treatment of Lupus Nephritis

Systemic lupus erythematosus (SLE) is a multi-organ inflammatory disease characterized by a significant morbidity and mortality related to both disease evolution as well as therapeutic side effects. At least half of SLE patients develop lupus nephritis. The inventors have used a Lyn -/- mouse model that develops an autoimmune disease exhibiting some...

Published: 7/30/2024 | Inventor(s): Nicolas Charles, Juan Rivera

Keywords(s): antibodies, Anti-IgE, Are, AUTOREACTIVE, IB3XXX, IBXXXX, IGE, IXXXXX, Lupus, Nephritis, Nephritis:, PATHOLOGICAL, Potential, treatment

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Immunology