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Potential Use of anti-IgE in the Treatment of Lupus Nephritis

Systemic lupus erythematosus (SLE) is a multi-organ inflammatory disease characterized by a significant morbidity and mortality related to both disease evolution as well as therapeutic side effects. At least half of SLE patients develop lupus nephritis. The inventors have used a Lyn -/- mouse model that develops an autoimmune disease exhibiting some...

Published: 7/30/2024 | Inventor(s): Nicolas Charles, Juan Rivera

Keywords(s): antibodies, Anti-IgE, Are, AUTOREACTIVE, IB3XXX, IBXXXX, IGE, IXXXXX, Lupus, Nephritis, Nephritis:, PATHOLOGICAL, Potential, treatment

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Immunology