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UTX LoxP Mouse Model for Oncology Research

UTX-flox. Conditional knockout mice for the histone demethylase UTX (Kdm6a) conditional knockout will help understand its role as a tumor suppressor. Di- and tri-methylations on histone H3 lysine 27 (H3K27me2 and H3K27me3) are epigenetic marks for gene repression. UTX (ubiquitously transcribed X chromosome protein), also known as Kdm6a (lysine (K)-specific...

Published: 4/8/2024 | Inventor(s): Kai Ge

Keywords(s): CCXXXX, CXXXXX, LOXP, Mouse, UTX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Research Materials