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Monoclonal Antibodies That Recognize the Human Type I Interferon Receptor and Block Interferon Signaling

Type I interferons play a critical role in both innate and adaptive immunity through the stimulation of the IFNAR1 which initiates interferon signaling in response to viral and bacterial infections. However, abnormal interferon signaling is associated with human diseases, such as lupus. The present invention discloses six hybridomas that produce mouse...

Published: 7/25/2024 | Inventor(s): Kirk Lubick, Shelly Robertson, Sonja Best

Keywords(s): antibodies, ANTI-HUMAN, DDXXXX, DXXXXX, IFNAR1, monoclonal, RXXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Research Materials