Search Results - anti-human

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Monoclonal Antibodies That Recognize the Human Type I Interferon Receptor and Block Interferon Signaling

Type I interferons play a critical role in both innate and adaptive immunity through the stimulation of the IFNAR1 which initiates interferon signaling in response to viral and bacterial infections. However, abnormal interferon signaling is associated with human diseases, such as lupus. The present invention discloses six hybridomas that produce mouse...

Published: 7/25/2024 | Inventor(s): Kirk Lubick, Shelly Robertson, Sonja Best

Keywords(s): antibodies, ANTI-HUMAN, DDXXXX, DXXXXX, IFNAR1, monoclonal, RXXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Research Materials

Antibodies Against TL1A, a TNF-Family Cytokine, for the Treatment and Diagnosis of Autoimmune Inflammatory Diseases

Autoimmune inflammatory diseases occur in greater than five percent of the United States population; this disease group includes asthma, multiple sclerosis, rheumatoid arthritis, and lupus. Treatments generally include immunosuppressants or anti-inflammatory drugs, which can have serious side effects; recently, more specific immunomodulatory therapies...

Published: 7/30/2024 | Inventor(s): Francoise Meylan, Yun-Jeong Song, Richard Siegel

Keywords(s): antibodies, ANTIBODY, ANTI-HUMAN, Anti-mouse, Autoimmune, diagnostic, DR3, IA3XXX, IAXXXX, IB3XXX, IBXXXX, Immunomodulation, immuno-modulator, immunomodulatory, INFLAMMATORY, inflammatory disease, IXXXXX, monoclonal, Monoclonal Antibodies, Monoclonal Antibody, Patent Category - Biotechnology, therapeutic, TL1A, tnf, TNFRSF25, TNFSF15, tumor necrosis factor, USES

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Immunology