Search Results - immunomodulatory

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A Murine Model of Inflammation Based on Chronic Expression of Interferon-Gamma

Abstract: An autoimmune disease is characterized by a malfunctioning healthy immune system mistakenly attacking healthy cells, tissues, and organs. These chronic diseases likely result from interactions between genetic and environmental factors. Gender, race, and ethnicity characteristics have been linked to the development of an autoimmune disease....

Published: 4/8/2024 | Inventor(s): Howard Young, Deborah Hodge

Keywords(s): Autoimmune, Autoinflammatory, IFNγ, immunomodulatory, immunostimulatory, Interferon gamma, Ovarian Failure Syndrome, Primary Biliary Cholangitis, Systemic lupus erythematosus, Young

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology

Anti-bacterial Treatments Using Peptide-Based Inhibitors of the STAT3-IL10 Pathway

Abstract: Tuberculosis (TB) is an infectious disease that typically affects the lungs. Current therapies include a panel of antibiotics given over a range of 6-9 months. As a result of the expense of treatment, the extended timeframe needed for effective treatment, and the scarcity of medicines in some developing countries, patient compliance with TB...

Published: 4/8/2024 | Inventor(s): Nadya Tarasova, Mercedes Gonzalez-Juarreto

Keywords(s): Anti-infective, IL-10, immunomodulatory, Immunotherapy, INTERLEUKIN, STAT3, TUBERCULOSIS

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease

Antibodies Against TL1A, a TNF-Family Cytokine, for the Treatment and Diagnosis of Autoimmune Inflammatory Diseases

Autoimmune inflammatory diseases occur in greater than five percent of the United States population; this disease group includes asthma, multiple sclerosis, rheumatoid arthritis, and lupus. Treatments generally include immunosuppressants or anti-inflammatory drugs, which can have serious side effects; recently, more specific immunomodulatory therapies...

Published: 7/30/2024 | Inventor(s): Francoise Meylan, Yun-Jeong Song, Richard Siegel

Keywords(s): antibodies, ANTIBODY, ANTI-HUMAN, Anti-mouse, Autoimmune, diagnostic, DR3, IA3XXX, IAXXXX, IB3XXX, IBXXXX, Immunomodulation, immuno-modulator, immunomodulatory, INFLAMMATORY, inflammatory disease, IXXXXX, monoclonal, Monoclonal Antibodies, Monoclonal Antibody, Patent Category - Biotechnology, therapeutic, TL1A, tnf, TNFRSF25, TNFSF15, tumor necrosis factor, USES

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Immunology