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National Cancer Institute Dosimetry System for Nuclear Medicine (NCINM) Computer Program

Abstract: Nuclear medicine is the second largest source of medical radiation exposure to the general population after computed tomography imaging. Imaging modalities utilizing nuclear medicine produce a more detailed view of internal structure and function and are most commonly used to diagnose diseases such as heart disease, Alzheimer’s and brain disorders....

Published: 5/8/2024 | Inventor(s):

Keywords(s): • National Cancer Institute Dosimetry System for Nuclear Med, Dosimetry, Lee, NCINM, Nuclear Medicine, Radiation, Radiation Dosing, SAF, Specific Absorbed Fraction

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Software / Apps, TherapeuticArea > Neurology

Levonorgestrel Butanoate Formulation and Methods Relating Thereto

Abstract: This invention is a potential subcutaneous or intramuscular progestin-only, injectable contraceptive for women. Forty-five percent (45%) of pregnancies in the United States are unintended. In this group, one-third of reproductive age women are obese – increasing the risk of diabetes, hypertension and venous thromboembolism (VTE). All these...

Published: 4/8/2024 | Inventor(s): Min Lee, Diana Blithe, Jia-Hwa Fang, Eduardo Ruiz, Ken Chen

Keywords(s): Blithe, CONTRACEPTIVE, INJECTABLE, LB, Lee, Levonorgestrel, Levonorgestrel Butanoate, LNG, National Institute of Child Health and Human Development, NICHD, Steroidal Progestin

Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Reproductive Health

Monomeric and Oligomeric Compounds as Contraceptives and Endocrine Therapeutics

Abstract: The options for male contraceptives are limited. Research is ongoing to develop a male contraceptive based on hormonal activity. Testosterone is one of the hormones necessary in producing sperm. Testosterone is absolutely required as a hormone for male fertility. Derivatives of testosterone for male contraceptives currently in clinical trials...

Published: 4/8/2024 | Inventor(s): Min Lee, Diana Blithe, Pranab Gupta, Bashir Kaskar, Ming-Teh Lin

Keywords(s): Blithe, CONTRACEPTIVE, Estrogenic Activity, Eunice Kennedy Shriver National Institute of Child Health an, Lee, Male Contraceptive, MONOMERIC, NCE, New Chemical Entity, NICHD, OLIGOMERIC

Category(s): Application > Therapeutics, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

New Heterocyclic Scaffold-Based Inhibitors of the Polo-Box Domain of Polo-like Kinase 1 for the Treatment of Cancer

Abstract: Polo-like kinase 1 (Plk1), a member of the Polo-like kinase family, plays a critical role in regulating mitosis and cell cycle progression. Aberrant expression of Plk1 has been observed in a variety of human cancers, and it is known to be associated with tumorigenesis as well as poor prognosis in cancer patients. Unlike normal cells, some...

Published: 4/8/2024 | Inventor(s): Kyung Lee, Kenneth Jacobson, Celeste Alverez, Jung-Eun Park

Keywords(s): CANCER, cell cycle, Heterocyclic Scaffold, Lee, mitosis, Oncology, PBD, plk1, Polo-Box Domain, Polo-Like Kinase 1, PRODRUGS, Triazoloquinazolinone

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology

National Cancer Institute dosimetry system for Computed Tomography (NCICT) Computer Program

Abstract: About half of the per capita dose of radiation due to medical exposures is provided by computed tomography (CT) examinations. Approximately 80 million CTs are performed annually in the United States. CT scans most commonly look for internal bleeding or clots, abscesses due to infection, tumors and internal structures. Although CT provides...

Published: 5/8/2024 | Inventor(s):

Keywords(s): • Computed Tomography, CT, CT Examination, Dosimetry, Lee, NCI dosimetry system for Computed Tomography, NCICT, Radiation, Radiation Dosing

Category(s): TherapeuticArea > Oncology, TherapeuticArea > Neurology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Software / Apps, TherapeuticArea > Infectious Disease