Search Results - plasmodium

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AMA1-RON2 Complex-Based Vaccine Against Malaria

This technology relates to a malaria vaccine composed of a protein complex of Apical Membrane Antigen (AMA1) and rhoptry neck protein 2 (RON2) with an adjuvant. AMA1 is a crucial component of the Plasmodium invasion machinery and is a leading candidate for antimalarial vaccine development. AMA1-based vaccines have shown ability to block red cell invasion...

Published: 7/25/2024 | Inventor(s): Louis Miller, Prakash Srinivasan

Keywords(s): Against, AMAI-RON2, CHALLENGE, COMPLEX, DC2XXX, Lethal, PLASMODIUM, Protection, PROVIDES, VACCINATION

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Vaccines

Transmission-Blocking Malaria Vaccine

There is no vaccine for malaria, and there is growing resistance to existing anti-malarial drugs. Sexual stage-specific antigens are of interest as vaccine candidates because disruption of these antigens would reduce the fertility and, thus, the infectivity of the parasite. This invention claims methods and compositions for delivering a Plasmodium...

Published: 7/25/2024 | Inventor(s): Alvaro Molina-Cruz, Carolina Barillas-Mury

Keywords(s): Anopheles, Critical, DA2XXX, DA5XXX, DAXXXX, DB2XXX, DB5XXX, DBXXXX, DC2XXX, DCXXXX, DD1XXX, DDXXXX, DEXXXX, DXXXXX, FALCIPARUM, Gambiae, Gene, Human, Malaria, Mosquitoes, Pfs47, PLASMODIUM, TRANSMISSION

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Research Materials

Erythroid Progenitor Cell Line for Hematological Disease Applications

Plasmodium vivax (malaria) is a significant health concern in many parts of Asia, Latin America, North Africa, and the Middle East. There is a lack of continuous culture systems for this pathogen. The subject technology is an erythroid progenitor continuous cell line (termed CD36E) identified by erythroid markers CD36, CD33, CD44, CD71, CD235, and...

Published: 7/25/2024 | Inventor(s): Ning Zhi, Neal Young, Susan Wong

Keywords(s): &, Blod, Blood, CD36E, Cell, Cells, continuous, DDXXXX, DISEASES, DXXXXX, Erythroid, Involving, Line, Malaria, Malaria (Plasmodium sp.), Patent Category - Biotechnology, PLASMODIUM, Potential, PRECURSORS, Progenitor, RED, Spp., STUDIES, termed, USES

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials, TherapeuticArea > Infectious Disease