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Ex-vivo Production of Regulatory B-Cells for Use in Auto-immune Diseases

Abstract: Regulatory B-cells (Breg) play an important role in reducing autoimmunity and reduced levels of these cells are implicated in etiology of several auto-inflammatory diseases. Despite their impact in many diseases, their physiological inducers are unknown. Given that Bregs are a very rare B-cell, identifying factors that promote their development...

Published: 8/14/2024 | Inventor(s): Charles Egwuagu, Ren-Wi Wang, Chengrong Yu

Keywords(s): ARTHRITIS, B-CELL, COLITIS, EYE, Multiple sclerosis, sarcoidosis

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology