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Inducible Activation Nucleic Acid Hybrid Switch for Conditional Generation of Oligonucleotides

Summary: The NCI is looking for innovative companies interested in co-developing and/or licensing a novel nucleic-based therapy based on the conditional activation strategy. Description of Technology: Gene therapy research has yielded FDA-approved treatments for an array of diseases. However, challenges facing nucleic-acid based therapeutics include...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Bruce Shapiro, Paul Zakrevsky

Keywords(s): Conditional Activation, Functional RNA, Gene silencing, In Silico Design, Nanoparticle, Nucleic Acid Therapeutic, RNA, RNA Logic, Shapiro

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics