Search Results - sjogren%27s

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Diagnostic Test and Therapeutic Target for Sjogren's Syndrome

Sjögren's syndrome is an autoimmune disease that attacks salivary glands resulting in chronic dry mouth and dry eyes. Currently, there is no single diagnostic test to confirm the presence of Sjögren's. Physicians presently reach diagnosis after conducting a series of blood and functional tests for tear and salivary production. Diagnosis is further...

Published: 7/25/2024 | Inventor(s): Melodie Weller, Hongen Yin, John (Jay) Chiorini

Keywords(s): Alteration, BMP6, Detection, Diagnosis, Expression, Gland, IA3XXX, IAXXXX, IXXXXX, LEVELS, Listed LPM Contreras as of 4/15/2015, Locally, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Salivary, Sjogren's, Syndrome, treatment

Category(s): TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials, Application > Therapeutics

AAV Mediated CTLA-4 Gene Transfer to Treat Sjogren's Syndrome

Sjögren’s syndrome is an autoimmune disease that affects over 2 million Americans, primarily over the age of 40. One of the major outcomes of Sjögren's syndrome is xerostomia (dry mouth) that is caused by immune system attack on moisture producing salivary glands. Researchers at the National Institute of Dental and Craniofacial Research have developed...

Published: 7/25/2024 | Inventor(s): John (Jay) Chiorini, Hongen Yin

Keywords(s): Adeno-associated, Adeno-associated Virus, IB3XXX, IBXXXX, IXXXXX, Sjogren's, Sjogren's syndrome, Syndrome, T-LYMPHOCYTE, virus, Xerostomia

Category(s): Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Immunology