Search Results - sukhbir+kaur

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Use of Anti-CD47 Antibodies for the Treatment of Cancer

Abstract: High expression of CD47, a cell surface receptor on several types of cancer cells, has been identified as a ‘don’t eat me signal’ that inhibits their killing by macrophages or NK cells. Conversely, the CD47 antibody B6H12 that blocks SIRPα binding enhances macrophage-dependent clearance of tumors in several mouse models, although others have...

Published: 4/8/2024 | Inventor(s): David Roberts, Sukhbir Kaur, Chengyu Liu

Keywords(s): CD47, Stem Cell

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology

Method for Generating Pluripotent and Multipotent Cells

Abstract: Research and clinical applications of induced pluripotent stem (iPS) cells are currently limited by reprogramming methods that may modify the host genome, and therefore be potentially unsafe and problematic for use in basic research, cell-based therapies, and drug-discovery applications. Researchers at the National Cancer Institute’s Laboratory...

Published: 4/8/2024 | Inventor(s): David Roberts, Sukhbir Kaur, Jeff Isenberg

Keywords(s): cell-based therapies, cell-reprogramming, iPS cells

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials