Search Results - jeff+isenberg

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Radioprotectants and Tumor Radiosensitizers Targeting Thrombospondin-1 and CD47

Abstract: The National Cancer Institute''s Laboratory of Pathology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize CD47-targeting agents as radioprotectants and tumor sensitizers. Radiation therapy not only damages cancer cells, but it also damages healthy...

Published: 4/8/2024 | Inventor(s): David Roberts, Justin Maxhimer, Jeff Isenberg

Keywords(s): CANCER, CD47, Morpholinos, Radioprotective Agents, Radiotherapeutics, Thrombospondin-1 (TSP1), Tumor Sensitizers

Category(s): Collaboration Sought > Licensing

Methods of preventing tissue ischemia

Abstract: The National Cancer Institute's Laboratory of Pathology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize therapeutics targeting vasodialation. Nitric oxide (NO) plays an important role as a major intrinsic vasodilator, and increases blood flow...

Published: 4/8/2024 | Inventor(s): Jeff Isenberg, David Roberts, William Frazier

Keywords(s): CD47, ISCHEMIA, nitric oxide, NO, THROMBOSPONDIN

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics

Method for Generating Pluripotent and Multipotent Cells

Abstract: Research and clinical applications of induced pluripotent stem (iPS) cells are currently limited by reprogramming methods that may modify the host genome, and therefore be potentially unsafe and problematic for use in basic research, cell-based therapies, and drug-discovery applications. Researchers at the National Cancer Institute’s Laboratory...

Published: 4/8/2024 | Inventor(s): David Roberts, Sukhbir Kaur, Jeff Isenberg

Keywords(s): cell-based therapies, cell-reprogramming, iPS cells

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials