Search Results - ips+cells

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Method for Generating Pluripotent and Multipotent Cells

Abstract: Research and clinical applications of induced pluripotent stem (iPS) cells are currently limited by reprogramming methods that may modify the host genome, and therefore be potentially unsafe and problematic for use in basic research, cell-based therapies, and drug-discovery applications. Researchers at the National Cancer Institute’s Laboratory...

Published: 4/8/2024 | Inventor(s): David Roberts, Sukhbir Kaur, Jeff Isenberg

Keywords(s): cell-based therapies, cell-reprogramming, iPS cells

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials

Metformin for the Treatment of Age-related Retinal Degeneration

Abstract: Retinal Degenerations (RD) are the leading cause of blindness in the United States. The degeneration of the Retinal Pigment Epithelium (RPE) is associated with various types of RD such as Stargardt’s disease, retinitis pigmentosa, choroideremia, Late-Onset Retinal Degeneration (L-ORD), and Age-related Macular Degeneration (AMD). The RPE as...

Published: 4/8/2024 | Inventor(s): Kapil Bharti, Kiyoharu Miyagishima, Fnu Ruchi, Justin Chang, Balendu Jha, Karla Barbosa-Sabenero, Katharina Clore-Gronenborn

Keywords(s): Age-related Macular Degeneration, AMD, Bharti, choroideremia, iPS cells, Late-Onset Retinal Degeneration, L-ORD, Metformin, RD, Retinal degeneration, Retinal Pigment Epithelium, Retinitis Pigmentosa, RPE, Stargardt’s disease

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat