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T-Cell Therapy Against Patient-Specific Cancer Mutations

Abstract: Human cancers contain genetic mutations that are unique to each patient. Some of the mutated peptides are immunogenic, can be recognized by T cells, and therefore, may serve as therapeutic targets. Scientists at the National Cancer Institute's Surgery Branch developed a method to identify T cells that specifically recognize immunogenic mutations...

Published: 4/8/2024 | Inventor(s): Eric Tran, Yong-Chen Lu, Paul Robbins, Steven Rosenberg

Keywords(s): Cholangiocarcinoma, Immunogenic, Rosenberg, T-cell, Tran

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology