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Enhanced Immunogenicity Against HIV-1 Using a DNA-prime Poxvirus Vaccination

Abstract: Researchers at the National Cancer Institute (NCI) have developed a method of stimulating an immune response in humans at risk for infection by, or already infected with, an Human Immunodeficiency Virus (HIV)-1 retrovirus. This method utilizes deoxyribonucleic acid (DNA) vaccines to stimulate CD8+ T cell immune responses. The DNA vaccine encodes...

Published: 8/5/2024 | Inventor(s): Genoveffa Franchini, Zdenek Hel, George Pavlakis, James Tartaglia

Keywords(s): Combination Therapy, CTL, cytotoxic T lymphocyte, Deoxyribonucleic Acid, DNA vaccine, Franchini, HIV, Human Immunodeficiency Virus, POX VIRUS

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, Application > Vaccines