Conformation Dependent Anti-major Outer Membrane Protein (MOMP) Monoclonal Antibody BD5

Description:
A murine hybridoma expressing mAb BD3 was found to react with a conformationally dependent epitope on the chlamydial Major Outer Membrane Protein (MOMP), a primary target of neutralizing antibodies and vaccine development. The BD3 neutralized the in vitro infectivity of C. trachomatis serovars B, Ba, D, E, L2. It is useful for verifying the correct conformation of MOMP in vaccines against chlamydia trachomatis, Serovars B, BA, D, E, AND L2.
Patent Information:
For Information, Contact:
Charles Rainwater
Technology Development Specialist
NIH Technology Transfer
301-496-5717
crainwater@mail.nih.gov
Inventors:
Harlan Caldwell
Keywords:
Against
ANTIBODY
Anti-major
B
ba
BD5
Chlamydia
CONFORMATION
Correct
D
Dependent
e
Hybridoma
L2
Listed LPM Thalhammer-Reyero as of 4/15/2015
Mab
MEMBRANE
MOMP
monoclonal
OUTER
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
Protein
RM
SEROVARS
TRACHOMATIS
USEFUL
vaccines
Verifying
WIXXXX
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