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Diagnostic and Therapeutic Use of Brother of the Regulator of Imprinted Sites (BORIS) Alternative Splice Forms
Case ID:
TAB-1556
Web Published:
12/6/2022
Description:
This technology identifies twenty five (25) new alternatively spliced transcripts of the BORIS gene. The transcripts lead to the expression of seventeen different protein isoforms with variable N- and C-termini encoded by BORIS gene locus. Differential expression levels of BORIS isoforms were observed in different cancers. While some BORIS alternative splice variants were expressed at different levels in all types of cancers, other expressed forms are specific to particular cancer(s).
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Direct Link:
https://nih.technologypublisher.com/tech/Diagnostic_and_Therapeutic_Use_of_Br other_of_the_Regulator_of_Imprinted_Sites_(BORIS)_Alternative_Splice_Forms
Category(s):
Collaboration
Licensing
Oncology
Immunology
Therapeutics
Diagnostics
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For Information, Contact:
Dawn Taylor-Mulneix
TTPS
NIH Technology Transfer
301-761-6958
dawn.taylor-mulneix@nih.gov
Inventors:
Victor Lobanenkov
Keywords:
Alternate
Boris
CA1AXX
CA1XXX
CANCER
CAXXXX
CB6XXX
CBXXXX
CXXXXX
Diagnostics
Forms
MULTIPLE
SPLICE
Tool
treatment
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