Formulation of a Modified Stable FGF-1 (TTHX1114) to Accelerate Corneal Endothelium Regeneration

Description:
This technology includes the use of a novel formulation for an engineered version of Fibroblast Growth Factor 1 (FGF1), TTHX1114, that can be used to accelerate regeneration of the corneal endothelium after surgical lesions. FGFs are well-established regulators of migration and proliferation of corneal endothelial cells (CECs).
Patent Information:
For Information, Contact:
Suryanarayana Vepa
Technology Licensing Specialist
NIH Technology Transfer
301-827-7181
sury.vepa@nih.gov
Inventors:
Vinay Vyas
Hui Fang Dong
Asaf Alimardanov
Gautam ("George") Mitra
Trevor Broadt
David Eveleth
Keywords:
FGF-1
FORMULATION
Modified
PRESERVATION
STABLE
TTHX1114
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