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Quantitative Measurement of Syndesmophytes in Ankylosing Spondylitis Using Computed Tomography (CT)
Case ID:
TAB-2304
Web Published:
12/6/2022
Description:
Syndesmophyte (abnormal bone) growth in the spine is a hallmark of Ankylosing Spondylitis, a type of inflammatory arthritis. Syndesmophyte growth is currently monitored using semi-quantitative scoring of radiographs, but radiographs consider only a small part of the vertebra, and the method is subject to reader error. Because syndesmophytes grow slowly, radiographs also lack sensitivity. The invention provides a method to measure syndesmophytes using data from computed tomography scans of the lumbar spine. It provides computer algorithm that fully quantitates syndesmophyte volumes in three-dimension space. This method allows precise and accurate measurement of the presence and rate of growth of syndesmophytes over time, which for the first time will permit testing of whether any treatments can slow the progression of this type of spinal arthritis.
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Direct Link:
https://nih.technologypublisher.com/tech/Quantitative_Measurement_of_Syndesmo phytes_in_Ankylosing_Spondylitis_Using_Computed_Tomography_(CT)
Category(s):
Collaboration
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For Information, Contact:
Vladimir Knezevic
Senior Advisor for Commercial Evaluations
NIH Technology Transfer
vlado.knezevic@nih.gov
Inventors:
Sovira Tan
Keywords:
AA3AXX
AA3XXX
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RADIOGRAPHY
Spondylitis
Syndesmophytes
tomography
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