Repurposing CDK Inhibitors for the Treatment of Zika Virus Infection

Description:
This invention includes the discovery and use of a group of CDK inhibitors that were found during a drug repurposing screen designed to find compounds that inhibit Zika virus caused cell death. The identified CDK inhibitors have all previously been used in clinical trials for other diseases, potentially reducing the long time course needed for new drug discovery and development.
Patent Information:
For Information, Contact:
Suryanarayana Vepa
Technology Licensing Specialist
NIH Technology Transfer
301-827-7181
sury.vepa@nih.gov
Inventors:
Ruili Huang
Miao Xu
Wenwei Huang
Hengli Tang
Emily Lee
Cheng YiChen
Yi Zhou
Hongjun Song
Guo-Li Ming
Zhexing Wen
Wei Zheng
Keywords:
CDK
Infection
Inhibitors
Repurposing
treatment
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virus
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WIXXXX
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Zika
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